[90] Sokolowska P, Janikiewicz J, Jastrzebska E, Brzozka Z, Dobrzyn A.: Combinations of regenerative medicine and Lab-on-a-chip systems: New hope to restoring the proper function of pancreatic islets in diabetes. Biosens Bioelectron. 2020 Jul 25;167:112451. doi: 10.1016/j.bios.2020.112451.

[89] Klak M, Gomółka M, Dobrzański T, Tymicki G, Cywoniuk P, Kowalska P, Kosowska K, Bryniarski T, Berman A, Dobrzyń A, Idaszek J, Święszkowski W, Wszoła M.: Irradiation with 365 nm and 405 nm wavelength shows differences in DNA damage of swine pancreatic islets. PLoS One. 2020;15(6):e0235052. doi: 10.1371/journal.pone.0235052. eCollection 2020.

[88] Dziewulska A, Dobosz AM, Dobrzyn A, Smolinska A, Kolczynska K, Ntambi JM, Dobrzyn P.: SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle. J Cell Physiol. 2020 Feb;235(2):1129-1140. doi: 10.1002/jcp.29026.

[87] Jazurek-Ciesiolka M, Janikiewicz J, Dobrzyn P, Dziewulska A, Kozinski K, Dobrzyn A.: Oleic acid increases the transcriptional activity of FoxO1 by promoting its nuclear translocation and β-catenin binding in pancreatic β-cells. Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2753-2764. doi: 10.1016/j.bbadis.2019.06.018. Epub 2019 Jun 27.

[86] Simoes ICM, Janikiewicz J, Bauer J, Karkucinska-Wieckowska A, Kalinowski P, Dobrzyń A, Wolski A, Pronicki M, Zieniewicz K, Dobrzyń P, Krawczyk M, Zischka H, Wieckowski MR, Potes Y.: Fat and Sugar-A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease. Nutrients. 2019 Nov 24;11(12):2871. doi: 10.3390/nu11122871.

[85] Dziewulska A, Dobosz AM, Dobrzyn A: High-Throughput Approaches onto Uncover (Epi)Genomic Architecture of Type 2 Diabetes. Genes (Basel). 2018;9(8). pii: E374. doi: 10.3390/genes9080374.

[84] Janikiewicz J, Pawelec P, Kucharczyk P, Dobrzyń A: The Good, the Bad, and the Ugly – role of the pancreas, endothelium, and adipose tissue axis in the management of pancreatic β-cell failure in obesity-related type 2 diabetes. Postepy Biochem 2018;64: 166-173.

[83] Komakula SSB, Tumova J, Kumaraswamy D, Burchat N, Vartanian V, Ye H, Dobrzyn A, Lloyd RS, Sampath H: The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue. Sci Rep. 2018;8(1): 14886. doi: 10.1038/s41598-018-33151-1.

[82]  Dobosz A, Dziewulska A, Dobrzyn A: Spotlight on epigenetics as a missing link between obesity and type 2 diabetes. Postepy Biochem 2018;64: 157-165.

[81] Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, Patalas-Krawczyk P, Borchard S, Jędrak P, Pierzynowska K, Szymański J, Wang DQ, Portincasa P, Węgrzyn G, Zischka H, Dobrzyn P, Bonora M, Duszynski J, Rimessi A, Karkucinska-Wieckowska A, Dobrzyn A, Szabadkai G, Zavan B, Oliveira PJ, Sardao VA, Pinton P, Wieckowski MR.: Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases. Int Rev Cell Mol Biol. 2018;340:209-344. doi: 10.1016/bs.ircmb.2018.05.006.

[80] Janikiewicz J, Szymański J, Malinska D, Patalas-Krawczyk P, Michalska B, Duszyński J, Giorgi C, Bonora M, Dobrzyn A, Wieckowski MR. Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics. Cell Death Dis. 2018;9(3):332.

[79] Vartanian V, Tumova J, Dobrzyn P, Dobrzyn A, Nakabeppu Y, Lloyd RS, Sampath H: 8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle. PLoS One. 2017 Jul 20;12(7):e0181687. doi: 10.1371/journal.pone.0181687.

[78] Szymański J, Janikiewicz J, Michalska B, Patalas-Krawczyk P, Perrone M, Ziółkowski W, Duszyński J, Pinton P, Dobrzyń A, Więckowski MR: Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure. Int J Mol Sci. 2017 Jul 20;18(7). pii: E1576. doi: 10.3390/ijms18071576.

[77] Kozinski K, Jazurek M, Dobrzyn P, Janikiewicz J, Kolczynska K, Gajda A, Dobrzyn A: Adipose- and muscle-derived Wnts trigger pancreatic β-cell adaptation to systemic insulin resistance. Sci Rep. 2016; 6:31553.

[76] Fendler W, Madzio J, Kozinski K, Patel K, Janikiewicz J, Szopa M, Tracz A, Borowiec M, Jarosz-Chobot P, Mysliwiec M, Szadkowska A, Hattersley AT, Ellard S, Malecki MT, Dobrzyn A, Mlynarski W: Differential regulation of serum microRNA expression by HNF1β and HNF1α transcription factors. Diabetologia. 2016; 59(7): 1463-1473.

[75] Mączewski M, Duda M, Marciszek M, Kołodziejczyk J, Dobrzyń P, Dobrzyń A, Mackiewicz U: Omega-3 Fatty Acids do not Protect Against Arrhythmias in Acute Nonreperfused Myocardial Infarction Despite Some Antiarrhythmic Effects. J Cell Biochem. 2016; doi: 10.1002/jcb.25550.

[74] Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Björklund P, Mackie K, Di Marzo V, Hökfelt TG, Dobrzyn A, Harkany T: Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015; 112(45): E6185-6194.

[73] Janikiewicz J, Hanzelka K, Dziewulska A, Kozinski K, Dobrzyn P, Bernas T, Dobrzyn A: Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells. J Lipid Res. 2015;56:1901-1911.

[72] Dobrzyn P, Bednarski T, Dobrzyn A. Metabolic reprogramming of the heart through stearoyl-CoA desaturase. Prog Lipid Res. 2015; 57:1-12.

[71] Janikiewicz J, Hanzelka K, Kozinski K, Kolczynska K, Dobrzyn A.: Islet β-cell failure in type 2 diabetes--Within the network of toxic lipids. Biochem Biophys Res Commun. 2015; 460(3):491-6.

[70] Malodobra-Mazur M, Dziewulska A, Kozinski K, Dobrzyn P, Kolczynska K, Janikiewicz J, Dobrzyn A: Stearoyl-CoA desaturase regulates inflammatory gene expression by changing DNA methylation level in 3T3 adipocytes. Int J Biochem Cell Biol. 2014;55:40-50.

[69] Dobrzyn P, Dobrzyn A: Stearoyl-CoA desaturase in the control of heart metabolism. In Stearoyl-CoA desaturase genes in lipid metabolism J.M. Ntambi (ed.) Springer, New York (2013), 85-101.

[68] Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A: CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. J Biol Chem. 2013, 288(45): 32685-32699.

[67] Dobrzyn P, Pyrkowska A, Duda MK, Bednarski T, Maczewski M, Langfort J, Dobrzyn A: Expression of lipogenic genes is upregulated in the heart with exercise-training induced but not pressure overload-induced left ventricular hypertrophy. Am J Physiol Endocrinol Metab 2013, 304(12): E1348-1358.

[66] MacDonald MH, Hasan NM, Dobrzyn A, Stocker SW, Ntambi JM, Liu X, Sampath H: Knockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cells. Arch Biochem Biophys 2013, 532(1): 23-31.

[65] Banach M, Malodobra-Mazur M, Gluba A, Katsiki N, Rysz J, Dobrzyn A: Statin therapy and new-onset diabetes: molecular mechanisms and clinical relevance. Curr Pharm Des 2013, 19(27): 4904-4912.

[64] Kozinski K, Dobrzyn A: Wnt signaling pathway - its role in regulation of cell metabolism. Postepy Hig Med Dosw. 2013; 67:1098-1108.

[63] Dobrzyn P, Pyrkowska A, Jazurek J, Dobrzyn A: Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acids oxidation. Mitochondrion 2012, 12:132-137.

[62] Dziewulska A, Dobrzyn P, Jazurek M, Pyrkowska A, Ntambi JM, Dobrzyn A: Monounsaturated fatty acids are required for membrane translocation of protein kinaase C-theta induced bylipid overload in skeletal muscle. Mol Membr Biol 2012, 29(7):309-320.

[61] Sztolsztener ME, Dobrzyn A, Pikula S, Tylki-Szymanska A, Bandorowicz-Pikula J: Impaired dynamics of the late endosomes/lysosome compartment in human Niemann-Pick type C skin fibroblast carrying mutation in NPC1 gene. Mol Biosyst. 2012, 8:1197-1205.

[60] Tylicki A, Siemieniuk M, Dobrzyn P, Ziolkowska G, Nowik M, Czyzewska U, Pyrkowska A: Fatty acid profile and influence of oxithiamine on fatty acid contetnt in Malassezia pachydermatis, Candida albicans and Saccharomyces cerevisiae. Mycoses 2012, 55:e106-113.

[59] Brzek P, Ksiazek A, Dobrzyn A, Konarzewski M: Effect of dietary restriction on metabolic, anatomic and molecular traits in mice depends on the initial level of basal metabolic rate (BMR). J Exp Biol 2012, 215:3191-3199.

[58] Ruminska A., Dobrzyn A.: The endocannabinoid system and its role in regulation of metabolizm in peripheral tissues. Postepy Biochem. 2012, 58(2):127-34

[57]  Dobrzyn P, Pyrkowska A, Jazurek M, Szymanski K, Langfort J, Dobrzyn A: Endurance training-induced accumulation of muscle triglicerides is coupled to upregulation of stearoyl-CoA desaturase 1. J Appl Physiol 2010, 109:1653-1661.

[56] Dobrzyn P, Dobrzyn A, Miyazaki M, Ntambi JM: Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice. J Lipid Res 2010,  51: 2202-2210.

[55] Dobrzyn P, Jazurek M, Dobrzyn A: Stearoyl-CoA desaturase and insulin resistance – What is the molecular switch. Biochim Biophys Acta - Bioenerg 2010, 1797: 1189-1194.

[54] Dobrzyn P, Dobrzyn A: Novel substituted heteroaromatic compounds as inhibitors of stearoyl-CoA desaturase. Expert Opin Ther Pat 2010, 20: 849-853.

[53] Dziewulska A, Dobrzyn P, Dobrzyn A: The role of AMP-activated protein kinase in regulation of skeletal muscle metabolism. Postepy Hig Med Dosw 2010, 64:513-521.

[52] Langfort J, Jagsz S, Dobrzyn P, Brzezinska Z, Klapcinska B, Galbo H, Gorski J.: Testosterone affects hormone-sesnsitive lipase (HSL) activity and lipid metabolism in the left ventricle. Biochem Biophys Res Commun. 2010, 399: 670-676.

[51] Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM: Stearoyl-CoA desaturas-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun. 2009, 380: 818-822.

[50] Dobrzyn P, Sampath H, Dobrzyn A, Miyazaki M, Ntambi JM: Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart. Am J Physiol Endocrinol Metab 2008, 294: E357-E364.

[49] Dobrzyn A, Dobrzyn P: Inhibition of stearoyl-CoA desaturase by cyclic amone derivatives. Expert Opin Ther Pat 2008, 18: 457-460.

[48] Dobrzyn P, Ntambi JM, Dobrzyn A: Stearoyl-CoA desaturase: A novel control point of lipid metabolism and insulin sensitivity. Eur J Lipid Sci Technol 2008, 110: 93-100.

[47] Jazurek M, Dobrzyn P, Dobrzyn A: Regulation of gene expression by long-chain fatty acids. Postepy Biochem. 2008, 54: 242-250.

[46] MacDonald MJ, Dobrzyn A, Ntambi JM, Stoker SW: The role of rapid lipogenesis in insulin secretion: Insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells. Arch Biochem Biophys 2008, 470: 153–162.

[45] Zarnowski R, Dobrzyn A, Ntambi JM, Woods JP: Ferrous, but not ferric iron maintains homeostasis in Histoplasma capsulatum triacylglycerides. Curr Microbiol 2008, 57: 153-157.

[44] Zarnowski R, Dobrzyn A, Ntambi JM, Woods JP: Neutral storage lipids of histoplasma capsulatum: Effect of culture age. Curr Microbiol 2008, 56: 110-114.

[43] Dobrzyn A: Toxic lipids. Academia 2009, 1: 8-11.

[42] Modrzejewski W, Knapp M, Dobrzyn A, Musial WJ, Gorski J: Ceramides and adhesive molecules in stable ischaemic heart disease. Przegl Lek 2008, 65: 131-134.

[41] Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM: Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary fat. J Biol Chem 2007, 282:2483-2493.

[40] Zarnowski R, Miyazaki M, Dobrzyn A, Ntambi JM, Woods JP: Typing of Histoplasma capsulatum strains by fatty acid profile analysis. J Med Microbiol 2007, 56: 788-797.

[39] Dobrzyn A, Dobrzyn P: Stearoyl-Co A desaturase – a new player in skeletal muscle metabolism regulation. J Physiol Pharmacol 2006, 57: 31-41.

[38] Dobrzyn A: Toksyczność lipidów, czyli dlaczego ludzie otyli cierpią na choroby metaboliczne. Czynn Ryz 2006, 3: 3-10.

[37] Dobrzyn P, Dobrzyn A: Stearoyl-CoA desaturase: a new therapeutic target of liver steatosis. Drug Develop Res 2006, 67: 643-650.

[36] Miyazaki M, Dobrzyn A, Elias PM, Ntambi JM: Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Proc Natl Acad Sci USA 2005, 102: 12501-12506.

[35] Dobrzyn A, Dobrzyn P, Miyazaki M, Sampath H, Chu K, Ntambi JM: Stearoyl-CoA desaturase 1 deficiency increases CTP: Choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver. J Biol Chem 2005, 280: 23356-23362.

[34] Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM: Stearoyl-CoA desaturase 1 deficiency reduces ceramide synthesis by down-regulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. Am J Physiol Endocrinol Metab 2005, 288: E599-E607.

[33] Dobrzyn A, Dobrzyn P, Miyazaki M, Ntambi JM: Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues. Biochem Biophys Res Commun 2005, 332: 892-896.

[32] Dobrzyn A, Ntambi JM: The role of stearoyl-CoA desaturase in the control of metabolism. Prostaglandins Leukot Essent Fatty Acids 2005, 75: 35-41.

[31] Dobrzyn A, Ntambi JM: Stearoyl-CoA desaturase as a new drug target for obesity treatment. Obes Rev 2005, 6: 169-174.

[30] Dobrzyn A, Ntambi J.M.: Stearoyl-CoA desaturase: a therapeutic target of insulin resistance and diabetes. Drug Discovery Today: Therapeutic strategies 2005, 2: 125-128.

[29] Rahman SM, Dobrzyn A, Lee SH, Dobrzyn P, Miyazaki M, Ntambi JM: Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J Physiol Endocrinol Metab 2005, 288: E381-E387.

[28] Knapp P, Dobrzyn A, Gorski J: Ceramide, sphinganine, sphingosine and acid sphingomyelinases in the human umbilical cord blood. Horm Metab Res 2005, 37: 433-437.

[27] Gorska M., Dobrzyn A, Baranowski M: Concentrations of sphingosine and sphinganine in plasma of patients with Type 2 diabetes. Med Sci Monit 2005, 11: CR35-CR38.

[26] Budlewska M, Gorska M, Dobrzyn A, Zendzian-Piotrowska M: Effect of prolonged exercise on esterification of blood-borne free fatty acids into lipids of the rat liver. Biol Sport 2005, 22: 181-189.

[25] Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM: Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proc Natl Acad Sci USA 2004, 101: 6409-6414.

[24] Miyazaki M, Dobrzyn A, Sampath H, Lee SH, Man WC, Chu K, Peters JM, Gonzalez FJ, Ntambi JM: Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-?. J Biol Chem 2004, 279: 35017-3502.

[23] Miyazaki M, Dobrzyn A, Man WC, Chu K, Sampath H, Kim HJ, Ntambi JM: Stearoyl-CoA desaturase gene 1 expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element binding protein-1c-dependent and independent mechanisms. J Biol Chem 2004, 279: 25164-25171.

[22] Lee SH, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM: Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis, but causes hypothermia in cold environment. J Lipid Res 2004, 1674-1682.

[21] Dobrzyn A, Ntambi JM: The role of stearoyl-CoA desaturase in body weight regulation. Trends Cardiovasc Med 2004, 14: 77-81.

[20] Asilmaz E, Cohen P, Miyazaki M, Dobrzyn P, Ueki K, Fayzikhodjaeva G, Soukas AA, Kahn CR, Ntambi JM, Socci ND, Friedman JM: Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. J Clin Invest 2004, 113: 414-424.

[19] Dobrzyn A, Zendzian-Piotrowska M, Gorski J: Effect of endurance training on the sphingomyelin signaling pathway activity in the skeletal muscles of the rat. J Physiol Pharmacol 2004, 55: 305-313.

[18] Wilson RA, Chang PK, Dobrzyn A, Ntambi JM, Zarnowski R, Keller NP: Two delta9-stearic acid desaturases are required for Aspergillus nidulans growth and development. Fungal Genet Biol 2004, 41: 501-509.

[17] Dobrzyn A, Knapp M, Gorski J: Effect of acute exercise and training on metabolism of ceramide in the heart muscle of the rat. Acta Physiol Scand 2004, 181: 313-319.
[16] Ntambi JM, Miyazaki M, Dobrzyn A: Regulation of stearoyl-CoA expression. Lipids 2004, 39: 1061-1065.

[15] Helge JW, Dobrzyn A, Saltin B, Gorski J: Exercise and training effects on ceramide metabolism in human skeletal muscle. Exp Physiol 2004, 89: 119-127.

[14] Gorska M, Dobrzyn A, Zendzian-Piotrowska M, Gorski J: Effect of streptozotocin-diabetes on the functioning of the sphingomyelin-signalling pathway in skeletal muscles of the rat. Horm Metab Res 2004, 36: 14-21.

[13] Strumilo S, Dobrzyn P, Czerniecki J, Tylicki A: Suicidal dephosphorylation of thiamine pyrophosphate coupled with pyruvate dehydrogenase complex. Ital J Biochem 2004, 53: 131-134.

[12] Rahman SM, Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Ntambi JM.: Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. Proc Natl Acad Sci USA 2003, 100: 11110-11115.

[11] Goldstein JT, Dobrzyn A, Clagett-Dame M, Pike W, DeLuca HF: Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor. Arch Biochem Biophys 2003, 420: 185-193.

[10] Gorska M, Baranczuk E, Dobrzyn A: Secretory Zn2+-dependent sphingomyelinase activity in the serum of patients with Type 2 diabetes is elevated. Horm Metab Res 2003, 35: 506-507.
[9] Dobrzyn A, Chocian G: Sphingomyelin signaling pathway – review. Med Metabol 2003, 7: 75-80.

[8] Gorska M, Dobrzyn A, Langfort J, Gorski J: Effect of hypothyreosis on the content of ceramides in rat tissues.  J Physiol Pharmacol 2003, 54: 89-97.

[7] Dobrzyn A, Gorski J: Ceramides and sphingomyelins in skeletal muscles of the rat: content and composition. Effect of prolonged exercise. Am J Physiol Endocrinol Metab 2002, 282: E277-E285.

[6] Dobrzyn A, Gorski J: Effect of acute exercise on the content of free sphinganine and sphingosine in different skeletal muscle types of the rat. Horm Metab Res 2002, 34: 523-529.

[5] Beresewicz A, Dobrzyn A, Gorski J: Accumulation of specific ceramides in ischemic/reperfused rat heart; effect of ischemic preconditioning. J Physiol Pharmacol 2002, 53: 371-382.

[4] Gorska M, Dobrzyn A, Zendzian-Piotrowska M, Namiot Z: Concentration and composition of free ceramides in human plasma. Horm Metab Res 2002, 34: 466-468.

[3] Gorski J, Dobrzyn A, Zendzian-Piotrowska M: The sphingomyelin-signaling pathway in skeletal muscles and its role in regulation of glucose uptake. Ann NY Acad Sci 2002, 967: 236-248.

[2] Gorska M, Dobrzyn A, Zendzian-Piotrowska M, Bucki R: Free ceramides in plasma of diabetes mellitus type 2. Med Metabol 2002, 4: 25-29.

[1] Zendzian-Piotrowska M, Gorska M, Dobrzyn A, Zabielski P: Effect of dexametazone on the content of ceramide and sphingomyelin in rat skeletal muscles. Pol J Endocrinol 2002, 53: 39-49.